Article
The dopamine receptor D1 gene is associated with the length of interval between first heroin use and onset of dependence in Chinese Han heroin addicts.
Journal of neural transmission (Vienna, Austria : 1996) - 1 Nov 2013
Peng Sufang, Du Jiang, Jiang Haifeng, Fu Yingmei, Chen Hanhui, Sun Haiming, Wang Dongxiang, Yu Shunying, Zhao Min
Abstract excerpt
Previous researches showed that the dopamine receptor D1 (DRD1) may play a critical role in drug dependence. This research aimed to determine whether DRD1 played a role in development of heroin dependence in Chinese heroin-dependent patients. 465 Chinese Han heroin-dependent subjects and 379 healthy controls were recruited in the Shanghai region. Five single-nucleotide-polymorphisms (SNPs) of the DRD1 gene were...
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