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Article

DRD3 variation associates with early-onset heroin dependence, but not specific personality traits.

Progress in neuro-psychopharmacology & biological psychiatry - 3 Jun 2014

Kuo Shin-Chang, Yeh Yi-Wei, Chen Chun-Yen, Huang Chang-Chih, Chang Hsin-An, Yen Che-Hung, Ho Pei-Shen, Liang Chih-Sung, Chou Han-Wei, Lu Ru-Band, Huang San-Yuan

Abstract excerpt

Dopamine D3 receptor-mediated pathways are involved in the mechanism of addiction, and genetic factors play a role in the vulnerability to heroin dependence. The aim of this study was to examine whether the corresponding gene, DRD3, is associated with the development of heroin dependence and specific personality traits in HD patients. Eight polymorphisms in DRD3 were analyzed in 1067 unrelated Han Chinese...

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Source

Identifiers

PMID: 24398431
DOI: 10.1016/j.pnpbp.2013.12.018

Genes

DRD3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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