Article
A 35.8 kilobases haplotype spanning ANKK1 and DRD2 is associated with heroin dependence in Han Chinese males.
Brain research - 1 Jun 2018
Zhang Jianbo, Yan Peng, Li Yunxiao, Cai Xintong, Yang Ziyu, Miao Xinyao, Chen Bo, Li Shengbin, Dang Wei, Jia Wei, Zhu Yongsheng
Abstract excerpt
Ankyrin repeat and kinase domain containing 1 (ANKK1) and dopamine receptor D2 (DRD2) gene polymorphisms have long been considered to contribute to susceptibility to heroin dependence. Despite their adjacent locations, few studies have elucidated the role of the potential interaction between ANKK1 and DRD2 in heroin dependence. In the present study, we performed a systematic analysis of the association between 39...
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