Article
Association studies of dopamine synthesis and metabolism genes with multiple phenotypes of heroin dependence.
BMC medical genetics - 31 Jul 2020
Li Yunxiao, Zhu Yongsheng, Lai Jianghua, Shi Xugang, Chen Yuanyuan, Zhang Jinyu, Wei Shuguang
Abstract excerpt
BACKGROUND: Heroin dependence is a complex disease with multiple phenotypes. Classification of heroin users into more homogeneous subgroups on the basis of these phenotypes could help to identify the involved genetic factors and precise treatments. This study aimed to identify the association between genetic polymorphisms of DA synthesis and metabolism genes, including tyrosine hydroxylase (TH), DOPA...
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