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Article

Pharmacogenomics of Anti-TNF Treatment Response Marks a New Era of Tailored Rheumatoid Arthritis Therapy.

International journal of molecular sciences - 21 Feb 2022

Wysocki Tomasz, Paradowska-Gorycka Agnieszka

Abstract excerpt

Rheumatoid arthritis (RA) is the most commonly occurring chronic inflammatory arthritis, the exact mechanism of which is not fully understood. Tumor Necrosis Factor (TNF)-targeting drugs has been shown to exert high effectiveness for RA, which indicates the key importance of this cytokine in this disease. Nevertheless, the response to TNF inhibitors varies, and approximately one third of RA patients are...

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Identifiers

PMID: 35216481
DOI: 10.3390/ijms23042366
PMCID: PMC8879844

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