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Genetic and Genomic Markers of Anti-TNF Treatment Response in Rheumatoid Arthritis

1 Jun 2015

Abstract excerpt

Despite the success of anti-TNF drugs in the treatment of rheumatoid arthritis, a significant rate of nonresponse remains. Current clinical factors confer little power for predicting response and, in current practice, an unsatisfactory 'trial and error' approach governs therapeutic decisions. Candidate gene and unbiased genome-wide investigations have sought to identify genetic biomarkers that predict who will...

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PMID: 26079957
DOI: 10.2217/bmm.15.18

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