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Article

The pancreatic β cell and type 1 diabetes: innocent bystander or active participant?

Trends in endocrinology and metabolism: TEM - 1 Jul 2013

Soleimanpour Scott A, Stoffers Doris A

Abstract excerpt

Type 1 diabetes mellitus (T1DM) is a chronic disease resulting from destruction of insulin-producing pancreatic β cells. Genetic and environmental factors contribute to T1DM onset. Use of high-throughput DNA sequencing has allowed geneticists to perform genome-wide association studies (GWAS) to identify novel gene loci associated with T1DM. Interestingly, >50% of these genes encode products that are expressed in...

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Identifiers

PMID: 23647931
DOI: 10.1016/j.tem.2013.03.005
PMCID: PMC3908840

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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