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Article

B cells in the spotlight: innocent bystanders or major players in the pathogenesis of type 1 diabetes.

Trends in endocrinology and metabolism: TEM - 1 Jan 2000

Silveira Pablo A, Grey Shane T

Abstract excerpt

It has long been established that type 1 diabetes (T1D) is a T cell-mediated autoimmune disease, with CD4+ and CD8+ T cells being largely responsible for the destruction of beta cells within the pancreatic islets of Langerhans. Although autoantibodies specific for islet cell proteins are regularly detected in individuals with T1D and can be utilized as effective markers for predicting the onset of disease, they...

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Share to Antigen-Presenting Cells
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16580840
DOI: 10.1016/j.tem.2006.03.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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