Article
A minimal transcriptional controlling network of regulatory T cell development.
The journal of physical chemistry. B - 24 Oct 2013
Liao Chen, Lu Ting
Abstract excerpt
Regulatory T cells (Treg) are a subpopulation of T cells that are central to immune homeostasis and develop under the control of a complex regulatory network consisting of FoxP3 and its partner factors. A central question about this network is how does it enable T cells to robustly specify and stably maintain their states despite intrinsic and environmental fluctuations. Inspired by recent experimental advances,...
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