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Article

The influence of assortativity on the robustness of signal-integration logic in gene regulatory networks.

Journal of theoretical biology - 7 Mar 2012

Pechenick Dov A, Payne Joshua L, Moore Jason H

Abstract excerpt

Gene regulatory networks (GRNs) drive the cellular processes that sustain life. To do so reliably, GRNs must be robust to perturbations, such as gene deletion and the addition or removal of regulatory interactions. GRNs must also be robust to genetic changes in regulatory regions that define the logic of signal-integration, as these changes can affect how specific combinations of regulatory signals are mapped to...

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Identifiers

PMID: 22155134
DOI: 10.1016/j.jtbi.2011.11.029
PMCID: PMC3265688

Genes

GRN

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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