Article

Flexible and scalable control of T cell memory by a reversible epigenetic switch

2022-12-31

Abstract excerpt

The immune system encodes information about the severity of a pathogenic threat in the quantity and type of memory cell populations formed in response. This encoding emerges from the decisions of lymphocytes to maintain or lose self-renewal and memory potential during a challenge. By tracking responding CD8 T cells at the single-cell and clonal lineage level using time-resolved transcriptomics and quantitative liv...

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Literature Corpus work: 82b0bada-b486-5607-9e16-2eed8345f9af
DOI: 10.1101/2022.12.31.521782

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