Article

Dynamical gene regulatory networks are tuned by transcriptional autoregulation with microRNA feedback

2020-02-03

Abstract excerpt

Concepts from dynamical systems theory, including multi-stability, oscillations, robustness and stochasticity, are increasingly implicated in the control of gene expression during cell fate decisions, inflammation and stem cell heterogeneity. However, the prevalence of the underlying structures within gene networks which drive these dynamical behaviours, such as direct autoregulation or feedback by microRNAs, is u...

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Literature Corpus work: 08c77942-c0c9-53d2-844e-4f0dff58d5a9
DOI: 10.1101/2020.02.03.932152

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