Article
Associations between genetic polymorphisms in IL-33, IL1R1 and risk for inflammatory bowel disease.
PloS one - 1 Jan 2013
Latiano Anna, Palmieri Orazio, Pastorelli Luca, Vecchi Maurizio, Pizarro Theresa T, Bossa Fabrizio, Merla Giuseppe, Augello Bartolomeo, Latiano Tiziana, Corritore Giuseppe, Settesoldi Alessia, Valvano Maria Rosa, D'Incà Renata, Stronati Laura, Annese Vito, Andriulli Angelo
Abstract excerpt
BACKGROUND: Recent evidence suggests that the IL-33/IL1RL1 axis plays a critical role in several autoimmune and inflammatory disorders; however, its mechanistic role in inflammatory bowel disease (IBD) has not been clearly defined. We investigated the contribution of IL-33 and IL1RL1 polymorphism...
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