Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Significance of IL-1RA Polymorphism in Iranian Patients with Inflammatory Bowel Disease.

Digestive diseases and sciences - 1 May 2015

Daryani Nasser Ebrahimi, Sadr Maryam, Moossavi Shirin, Shahkarami Sepideh, Soltani Samaneh, Farhadi Elham, Rezaei Nima

Abstract excerpt

BACKGROUND AND AIM: Interleukin (IL)-1 family members play an important role in the pathogenesis of inflammatory bowel disease (IBD). There are conflicting results regarding the association of IL-1 gene cluster single nucleotide polymorphisms (SNPs) with IBD and its clinical features. The aim of this study was to examine IL-1α -889 C/T, IL-1β -511 C/T, IL-1β +3962 C/T, IL-1R Pst-I1970 C/T, and IL-1RA Mspa-I11100...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Colitis, Ulcerative
Share to Crohn Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunosuppressive Agents

Share to Interleukin 1 Receptor Antagonist Protein

Share to Interleukin-1alpha

Share to Interleukin-1beta

Share to Severity of Illness Index

Source

Identifiers

PMID: 25466956
DOI: 10.1007/s10620-014-3457-z

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Significance of IL-1RA Polymorphism in Iranian Patients with Inflammatory Bowel Disease.PMID 25466956Read ↗

Associations between Gene Polymorphisms in Pro-inflammatory Cytokines and the Risk of Inflammatory Bowel Disease: A Meta-analysis.Semantic proximity Read ↗

The -2518 A/G MCP-1 polymorphism as a risk factor of inflammatory bowel disease.Semantic proximity Read ↗

Role of tumor necrosis factor-alpha (C-863A) polymorphism in pathogenesis of inflammatory bowel disease in Northern India.Semantic proximity Read ↗

Significance of interleukin-1beta and interleukin-1 receptor antagonist genetic polymorphism in inflammatory bowel diseases.Semantic proximity Read ↗

Evaluation of tumor necrosis factor (TNF)-α mRNA expression level and the rs1799964 polymorphism of the TNF-α gene in peripheral mononuclear cells of patients with inflammatory bowel diseasesSemantic proximity Read ↗

MDR1 polymorphisms are associated with inflammatory bowel disease in a cohort of Croatian IBD patients.Semantic proximity Read ↗

Interleukin 1 β (IL-1B) and IL-1 antagonist receptor (IL-1RN) gene polymorphisms are associated with the genetic susceptibility and steroid dependence in patients with ulcerative colitis.Semantic proximity Read ↗

Association of interleukin-1 family gene polymorphisms with juvenile idiopathic arthritis in Iranian population.Semantic proximity Read ↗

Polymorphisms of the IL-1beta and IL-1beta-inducible genes in ulcerative colitis.Semantic proximity Read ↗

Inflammatory cytokine gene polymorphism profiles in Turkish patients with ulcerative colitis.Semantic proximity Read ↗

Relationship between IL-10 gene -819C/T polymorphism and the risk of inflammatory bowel disease: a meta-analysis.Semantic proximity Read ↗

Interleukin and interleukin receptor gene polymorphisms in inflammatory bowel diseases susceptibility.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.