Article
Genome-wide pathway-based quantitative multiple phenotypes analysis.
PloS one - 1 Jan 2020
Deng Yamin, Wu Shiman, Fan Huifang
Abstract excerpt
For complex diseases, genome-wide pathway association studies have become increasingly promising. Currently, however, pathway-based association analysis mainly focus on a single phenotype, which may insufficient to describe the complex diseases and physiological processes. This work proposes a combination model to evaluate the association between a pathway and multiple phenotypes and to reduce the run time based...
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