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Article

Comparing partial least square approaches in a gene- or region-based association study for multiple quantitative phenotypes.

Human biology - 1 Jan 2014

Yuan Zhongshang, Zhang Xiaoshuai, Li Fangyu, Zhao Jinghua, Xue Fuzhong

Abstract excerpt

On thinking quantitatively of complex diseases, there are at least three statistical strategies for association studies: one single-nucleotide polymorphism (SNP) on a single trait, gene or region (with multiple SNPs) on a single trait, and gene or region on multiple traits. The third approach is the most general in dissecting genetic mechanisms underlying complex diseases underpinning multiple quantitative...

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Identifiers

PMID: 25401986
DOI: 10.3378/027.086.0106

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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