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Article

Enhanced thermostability of keratinase by computational design and empirical mutation.

Journal of industrial microbiology & biotechnology - 1 Jul 2013

Liu Baihong, Zhang Juan, Fang Zhen, Gu Lei, Liao Xiangru, Du Guocheng, Chen Jian

Abstract excerpt

Keratinases are proteolytic enzymes capable of degrading insoluble keratins. The importance of these enzymes is being increasingly recognized in fields as diverse as animal feed production, textile processing, detergent formulation, leather manufacture, and medicine. To enhance the thermostability of Bacillus licheniformis BBE11-1 keratinase, the PoPMuSiC algorithm was applied to predict the folding free energy...

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PMID: 23619970
DOI: 10.1007/s10295-013-1268-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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