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Article

Identification of amino acid residues responsible for increased thermostability of feruloyl esterase A from Aspergillus niger using the PoPMuSiC algorithm.

Bioresource technology - 1 Jan 2011

Zhang Shuai-Bing, Wu Zhong-Liu

Abstract excerpt

Feruloyl esterases are key enzymes involved in the complete hydrolysis of hemicellulose. In order to improve the thermostability of feruloyl esterase A (FaeA) from Aspergillus niger CIB 423.1, the PoPMuSiC algorithm was applied to predict the folding free energy change (ΔΔG) of amino acid substitutions. Four amino acid substitutions (S92A, D93G, D174A and S187F) were introduced into the enzyme by site-directed...

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PMID: 20801026
DOI: 10.1016/j.biortech.2010.08.019

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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