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Article

Improvement in organic solvent resistance of keratinase BLk by directed evolution.

Journal of biotechnology - 20 Feb 2024

Zhu Fucheng, Yan Zixu, Dai Jingli, Li Guosi, Xu Qilin, Ma Yunfeng, Ma Jingbo, Chen Naidong, Zhang Xinhong, Zang Yongjun

Abstract excerpt

Keratinase, a vital enzyme in hair degradation, requires enhanced stability for industrial applications in the harsh reaction environment used for keratin hydrolysis. Previous studies have focused on improving keratinase thermostability. In this study, directed evolution was applied to enhance the organic solvent stability of the keratinase BLk from Bacillus licheniformis. Three mutants were identified,...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 38244699
DOI: 10.1016/j.jbiotec.2024.01.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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