Genome-wide association study signal at the 12q12 locus for Crohn's disease may represent associations with the MUC19 gene.

doi:10.1097/MIB.0b013e318281f454

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Article

Genome-wide association study signal at the 12q12 locus for Crohn's disease may represent associations with the MUC19 gene.

Inflammatory bowel diseases - 1 May 2013

Kumar Vijay, Mack David R, Marcil Valerie, Israel David, Krupoves Alfreda, Costea Irina, Lambrette Philippe, Grimard Guy, Dong Jinsong, Seidman Ernest G, Amre Devendra K, Levy Emile

Abstract excerpt

BACKGROUND: Genome-wide association studies (GWAS) in Crohn's disease (CD) have identified associations with single-nucleotide polymorphism (SNP) rs11175593 at chromosome 12q12. The MUC19 and LRRK2 genes reside close to the GWAS signal, but it is as yet unclear which of the 2 genes represent the CD susceptibility genes. METHODS: We studied associations between nonsynonymous coding variants in the MUC19 (5) and...

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PMID: 23619718
DOI: 10.1097/MIB.0b013e318281f454

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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