Article
Investigation of Crohn's disease risk loci in ulcerative colitis further defines their molecular relationship.
Gastroenterology - 1 Feb 2009
Anderson Carl A, Massey Dunecan C O, Barrett Jeffrey C, Prescott Natalie J, Tremelling Mark, Fisher Sheila A, Gwilliam Rhian, Jacob Jemima, Nimmo Elaine R, Drummond Hazel, Lees Charlie W, Onnie Clive M, Hanson Catherine, Blaszczyk Katarzyna, Ravindrarajah Radhi, Hunt Sarah, Varma Dhiraj, Hammond Naomi, Lewis Gregory, Attlesey Heather, Watkins Nick, Ouwehand Willem, Strachan David, McArdle Wendy, Lewis Cathryn M, Lobo Alan, Sanderson Jeremy, Jewell Derek P, Deloukas Panos, Mansfield John C, Mathew Christopher G, Satsangi Jack, Parkes Miles
Abstract excerpt
BACKGROUND & AIMS: Identifying shared and disease-specific susceptibility loci for Crohn's disease (CD) and ulcerative colitis (UC) would help define the biologic relationship between the inflammatory bowel diseases. More than 30 CD susceptibility loci have been identified. These represent important candidate susceptibility loci for UC. Loci discovered by the index genome scans in CD have previously been tested...
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