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Article

Noise and interlocking signaling pathways promote distinct transcription factor dynamics in response to different stresses.

Molecular biology of the cell - 1 Jun 2013

Petrenko Natalia, Chereji Razvan V, McClean Megan N, Morozov Alexandre V, Broach James R

Abstract excerpt

All cells perceive and respond to environmental stresses through elaborate stress-sensing networks. Yeast cells sense stress through diverse signaling pathways that converge on the transcription factors Msn2 and Msn4, which respond by initiating rapid, idiosyncratic cycles into and out of the nucleus. To understand the role of Msn2/4 nuclear localization dynamics, we combined time-lapse studies of Msn2-GFP...

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Identifiers

PMID: 23615444
DOI: 10.1091/mbc.E12-12-0870
PMCID: PMC3681706

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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