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Article

Yeast cell fate control by temporal redundancy modulation of transcription factor paralogs.

Nature communications - 25 May 2021

Wu Yan, Wu Jiaqi, Deng Minghua, Lin Yihan

Abstract excerpt

Recent single-cell studies have revealed that yeast stress response involves transcription factors that are activated in pulses. However, it remains unclear whether and how these dynamic transcription factors temporally interact to regulate stress survival. Here we show that budding yeast cells can exploit the temporal relationship between paralogous general stress regulators, Msn2 and Msn4, during stress...

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PMID: 34035307
DOI: 10.1038/s41467-021-23425-0
PMCID: PMC8149833

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