Article
Genomics of cellular proliferation in periodic environmental fluctuations.
Molecular systems biology - 5 Mar 2018
Salignon Jérôme, Richard Magali, Fulcrand Etienne, Duplus-Bottin Hélène, Yvert Gaël
Abstract excerpt
Living systems control cell growth dynamically by processing information from their environment. Although responses to a single environmental change have been intensively studied, little is known about how cells react to fluctuating conditions. Here, we address this question at the genomic scale by measuring the relative proliferation rate (fitness) of 3,568 yeast gene deletion mutants in out-of-equilibrium...
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