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Article

Human brain imaging studies of DISC1 in schizophrenia, bipolar disorder and depression: a systematic review.

Schizophrenia research - 1 Jun 2013

Duff Barbara J, Macritchie Karine A N, Moorhead Thomas W J, Lawrie Stephen M, Blackwood Douglas H R

Abstract excerpt

Disrupted-in-Schizophrenia 1 (DISC1) is a well researched candidate gene for schizophrenia and affective disorders with a range of functions relating to neurodevelopment. Several human brain imaging studies investigating correlations between common and rare variants in DISC1 and brain structure and function have shown conflicting results. A meta-analysis of case/control data showed no association between...

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Source

Identifiers

PMID: 23602339
DOI: 10.1016/j.schres.2013.03.015

Genes

DISC1
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Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Human brain imaging studies of DISC1 in schizophrenia, bipolar disorder and depression: a systematic review.PMID 23602339Read ↗

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DISC1 is associated with prefrontal cortical gray matter and positive symptoms in schizophrenia.Semantic proximity Read ↗

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Association analysis of the DISC1 gene with schizophrenia in the Japanese population and DISC1 immunoreactivity in the postmortem brain.Semantic proximity Read ↗

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