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DISC1 in Schizophrenia: Genetic Mouse Models and Human Genomic Imaging

13 Dec 2010

Abstract excerpt

Schizophrenia and related disorders have a major genetic component. Several large-scale studies have uncovered a number of possible candidate genes, but these have yet to be consistently replicated and their underlying biological function remains elusive. One exception is 'Disrupted in schizophrenia 1' (DISC1), a gene locus originally identified in a large Scottish family, showing a heavy burden of major mental...

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PMID: 21149852
DOI: 10.1093/schbul/sbq135

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