Article
A brain-wide association study of DISC1 genetic variants reveals a relationship with the structure and functional connectivity of the precuneus in schizophrenia.
Human brain mapping - 1 Nov 2014
Gong Xiaohong, Lu Wenlian, Kendrick Keith M, Pu Weidan, Wang Chu, Jin Li, Lu Guangmin, Liu Zhening, Liu Haihong, Feng Jianfeng
Abstract excerpt
The Disrupted in Schizophrenia Gene 1 (DISC1) plays a role in both neural signaling and development and is associated with schizophrenia, although its links to altered brain structure and function in this disorder are not fully established. Here we have used structural and functional MRI to investigate links with six DISC1 single nucleotide polymorphisms (SNPs). We employed a brain-wide association analysis...
Topics
Join the communities discussing this publication.