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Article

Increasing power by using haplotype similarity in a multimarker transmission/disequilibrium test.

Journal of bioinformatics and computational biology - 1 Apr 2013

Abad-Grau María M, Medina-Medina Nuria, Moral Serafín, Montes-Soldado Rosana, Torres-Sánchez Sergio, Matesanz Fuencisla

Abstract excerpt

It is already known that power in multimarker transmission/disequilibrium tests may improve with the number of markers as some associations may require several markers to be captured. However, a mechanism such as haplotype grouping must be used to avoid incremental complexity with the number of markers. 2G, a state-of-the-art transmission/disequilibrium test, implements this mechanism to its maximum extent by...

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PMID: 23600811
DOI: 10.1142/S021972001250014X

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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