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Article

Sample reproducibility of genetic association using different multimarker TDTs in genome-wide association studies: characterization and a new approach.

PloS one - 1 Jan 2012

Abad-Grau Mara M, Medina-Medina Nuria, Montes-Soldado Rosana, Matesanz Fuencisla, Bafna Vineet

Abstract excerpt

Multimarker Transmission/Disequilibrium Tests (TDTs) are very robust association tests to population admixture and structure which may be used to identify susceptibility loci in genome-wide association studies. Multimarker TDTs using several markers may increase power by capturing high-degree associations. However, there is also a risk of spurious associations and power reduction due to the increase in degrees of...

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PMID: 22363405
DOI: 10.1371/journal.pone.0029613
PMCID: PMC3281822

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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