Article
A new association test using haplotype similarity.
Genetic epidemiology - 1 Sept 2007
Sha Qiuying, Chen Huann-Sheng, Zhang Shuanglin
Abstract excerpt
Association tests based on multi-marker haplotypes may be more powerful than those based on single markers. The existing association tests based on multi-marker haplotypes include Pearson's chi2 test which tests for the difference of haplotype distributions in cases and controls, and haplotype-similarity based methods which compare the average similarity among cases with that of the controls. In this article, we...
Topics
- Algorithms
- Alleles
- Computer Simulation
- Cystic Fibrosis
- Data Interpretation, Statistical
- Genetic Markers
- Genotype
- Haplotypes
- Humans
- Models, Genetic
- Models, Statistical
- Risk