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Article

Increasing power in association studies by using linkage disequilibrium structure and molecular function as prior information.

Genome research - 1 Apr 2008

Eskin Eleazar

Abstract excerpt

The availability of various types of genomic data provides an opportunity to incorporate this data as prior information in genetic association studies. This information includes knowledge of linkage disequilibrium structure as well as which regions are likely to be involved in disease. In this paper, we present an approach for incorporating this information by revisiting how we perform multiple-hypothesis...

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Share to Data Interpretation, Statistical
Share to Genetic Markers
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genome, Human

Share to Genomics

Share to Linkage Disequilibrium

Share to Oligonucleotide Array Sequence Analysis

Share to Polymorphism, Genetic

Source

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Identifiers

PMID: 18353808
DOI: 10.1101/gr.072785.107
PMCID: PMC2279252

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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