Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association testing strategy for data from dense marker panels.

PloS one - 1 Jan 2013

Lee Donghyung, Bacanu Silviu-Alin

Abstract excerpt

Genome wide association studies have been usually analyzed in a univariate manner. The commonly used univariate tests have one degree of freedom and assume an additive mode of inheritance. The experiment-wise significance of these univariate statistics is obtained by adjusting for multiple testing. Next generation sequencing studies, which assay 10-20 million variants, are beginning to come online. For these...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Algorithms
Share to Computational Biology
Share to Computer Simulation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Data Mining

Share to Genetic Association Studies

Share to High-Throughput Nucleotide Sequencing

Share to Linkage Disequilibrium

Share to Models, Statistical

Source

Open in PubMed Open full text

Identifiers

PMID: 24265830
DOI: 10.1371/journal.pone.0080540
PMCID: PMC3827222

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association testing strategy for data from dense marker panels.PMID 24265830Read ↗

Association methods in human genetics.Semantic proximity Read ↗

Dynamic Bayesian testing of sets of variants in complex diseases.Semantic proximity Read ↗

Evaluating and improving power in whole-genome association studies using fixed marker sets.Semantic proximity Read ↗

Robust and powerful tests for rare variants using Fisher's method to combine evidence of association from two or more complementary tests.Semantic proximity Read ↗

Statistics to prioritize rare variants in family-based sequencing studies with disease subtypesSemantic proximity Read ↗

Single Marker Family-Based Association Analysis Conditional on Parental Information.Semantic proximity Read ↗

Single-marker family-based association analysis conditional on parental information.Semantic proximity Read ↗

Statistics to prioritize rare variants in family-based sequencing studies with disease subtypes.Semantic proximity Read ↗

Power of single- vs. multi-marker tests of association.Semantic proximity Read ↗

[Family-based association tests for rare variants].Semantic proximity Read ↗

Genome-wide association filtering using a highly locus-specific transmission/disequilibrium test.Semantic proximity Read ↗

A flexible approach for the analysis of rare variants allowing for a mixture of effects on binary or quantitative traits.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.