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Article

Engineering microbial phenotypes through rewiring of genetic networks.

Nucleic acids research - 5 May 2017

Windram Oliver P F, Rodrigues Rui T L, Lee Sangjin, Haines Matthew, Bayer Travis S

Abstract excerpt

The ability to program cellular behaviour is a major goal of synthetic biology, with applications in health, agriculture and chemicals production. Despite efforts to build 'orthogonal' systems, interactions between engineered genetic circuits and the endogenous regulatory network of a host cell can have a significant impact on desired functionality. We have developed a strategy to rewire the endogenous cellular...

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Identifiers

PMID: 28369627
DOI: 10.1093/nar/gkx197
PMCID: PMC5416768

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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