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Article

Different levels of catabolite repression optimize growth in stable and variable environments.

PLoS biology - 1 Jan 2014

New Aaron M, Cerulus Bram, Govers Sander K, Perez-Samper Gemma, Zhu Bo, Boogmans Sarah, Xavier Joao B, Verstrepen Kevin J

Abstract excerpt

Organisms respond to environmental changes by adapting the expression of key genes. However, such transcriptional reprogramming requires time and energy, and may also leave the organism ill-adapted when the original environment returns. Here, we study the dynamics of transcriptional reprogramming and fitness in the model eukaryote Saccharomyces cerevisiae in response to changing carbon environments. Population...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24453942
DOI: 10.1371/journal.pbio.1001764
PMCID: PMC3891604

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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