Evolution of transcriptional regulatory networks in yeast populations.

Abstract excerpt

Saccharomyces cerevisiae is the most thoroughly studied eukaryote at the cellular, molecular, and genetic level. Recent boost in whole-genome sequencing, array-based allelic variation mapping, and genome-wide transcriptional profiling have unprecedentedly advanced knowledge on cell biology and evolution of this organism. It is now possible to investigate how evolution shapes the functional architecture of yeast...

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