Article
How Transcription Networks Evolve and Produce Biological Novelty.
Cold Spring Harbor symposia on quantitative biology - 1 Jan 2015
Nocedal Isabel, Johnson Alexander D
Abstract excerpt
The rewiring of gene regulatory networks over evolutionary timescales produces changes in the patterns of gene expression and is a major source of diversity among species. Yet the molecular mechanisms underlying evolutionary rewiring are only beginning to be understood. Here, we discuss recent analyses in ascomycete yeasts that have revealed several general principles of network rewiring. Specifically, we discuss...
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