Article
Cytokine polymorphisms in the pathophysiology of mood disorders.
CNS spectrums - 1 Aug 2009
Clerici Mario, Arosio Beatrice, Mundo Emanuela, Cattaneo Elisabetta, Pozzoli Sara, Dell'osso Bernardo, Vergani Carlo, Trabattoni Daria, Altamura A Carlo
Abstract excerpt
INTRODUCTION: An increasing amount of data suggests that dysregulation of the immune system, including the cytokine network, is associated with the etiology and pathophysiology of mood disorders. Genes encoding cytokines are highly polymorphic and single nucleotide polymorphisms, associated with increased or reduced cytokine production, have been described. The aim of this study was to define the genetic...
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