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Article

D316 is critical for the enzymatic activity and HIV-1 restriction potential of human and rhesus APOBEC3B.

Virology - 20 Jun 2013

McDougle Rebecca M, Hultquist Judd F, Stabell Alex C, Sawyer Sara L, Harris Reuben S

Abstract excerpt

APOBEC3B is one of seven human APOBEC3 DNA cytosine deaminases that function to inhibit the replication and persistence of retroelements and retroviruses. Human APOBEC3B restricts the replication of HIV-1 in HEK293 cells, while our laboratory clone of rhesus macaque APOBEC3B did not. We mapped th...

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Identifiers

PMID: 23542011
DOI: 10.1016/j.virol.2013.03.003
PMCID: PMC3752335

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23542011-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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