Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evolution of the primate APOBEC3A cytidine deaminase gene and identification of related coding regions.

PloS one - 1 Jan 2012

Henry Michel, Terzian Christophe, Peeters Martine, Wain-Hobson Simon, Vartanian Jean-Pierre

Abstract excerpt

The APOBEC3 gene cluster encodes six cytidine deaminases (A3A-C, A3DE, A3F-H) with single stranded DNA (ssDNA) substrate specificity. For the moment A3A is the only enzyme that can initiate catabolism of both mitochondrial and nuclear DNA. Human A3A expression is initiated from two different meth...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to APOBEC-3G Deaminase
Share to Chromosomes, Human, Pair 4
Share to Codon

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytidine Deaminase

Share to HeLa Cells

Share to Microscopy, Fluorescence

Share to Primates

Share to Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 22272271
DOI: 10.1371/journal.pone.0030036
PMCID: PMC3260193

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22272271-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evolution of the primate APOBEC3A cytidine deaminase gene and identification of related coding regions.PMID 22272271Read ↗

Orthologous mammalian APOBEC3A cytidine deaminases hypermutate nuclear DNA.Semantic proximity Read ↗

Clustered mutations in hominid genome evolution are consistent with APOBEC3G enzymatic activity.Semantic proximity Read ↗

Divergence in dimerization and activity of primate APOBEC3CSemantic proximity Read ↗

Loop 1 of APOBEC3C regulates its antiviral activity against HIV-1Semantic proximity Read ↗

Recurrent Loss of APOBEC3H Activity during Primate EvolutionSemantic proximity Read ↗

APOBEC3 family proteins as drivers of virus evolutionSemantic proximity Read ↗

Adaptive evolution and antiviral activity of the conserved mammalian cytidine deaminase APOBEC3H.Semantic proximity Read ↗

Recurrent Loss of APOBEC3H Activity during Primate Evolution.Semantic proximity Read ↗

Retroviruses drive the rapid evolution of mammalian APOBEC3 genes.Semantic proximity Read ↗

Role of the single deaminase domain APOBEC3A in virus restriction, retrotransposition, DNA damage and cancerSemantic proximity Read ↗

Divergence in Dimerization and Activity of Primate APOBEC3C.Semantic proximity Read ↗

Ancient adaptive evolution of the primate antiviral DNA-editing enzyme APOBEC3G.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.