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Article

Adaptive evolution and antiviral activity of the conserved mammalian cytidine deaminase APOBEC3H.

Journal of virology - 1 Apr 2006

OhAinle Molly, Kerns Julie A, Malik Harmit S, Emerman Michael

Abstract excerpt

The APOBEC3 genes encode cytidine deaminases that act as components of an intrinsic immune defense that have potent activity against a variety of retroelements. This family of genes has undergone a rapid expansion from one or two genes in nonprimate mammals to at least seven members in primates. Here we describe the evolution and function of an uncharacterized antiviral effector, APOBEC3H, which represents the...

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Identifiers

PMID: 16571802
DOI: 10.1128/JVI.80.8.3853-3862.2006
PMCID: PMC1440450

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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