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Article

Tyrosine 284 phosphorylation is required for ClC-3 chloride channel activation in vascular smooth muscle cells.

Cardiovascular research - 1 Jun 2013

Wang Xiao-Guang, Tao Jing, Ma Ming-Ming, Tang Yong-Bo, Zhou Jia-Guo, Guan Yong-Yuan

Abstract excerpt

AIMS: The ClC-3 chloride channel (and current, ICl,ClC-3) plays an important role in cell volume regulation, proliferation, and apoptosis in vascular smooth muscle cells, and is a potential target for prevention of vascular remodelling and stroke. However, modulation of ICl,ClC-3 by intercellular...

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Source

Identifiers

PMID: 23536605
DOI: 10.1093/cvr/cvt063

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23536605-2026-09-04.1. Manifest publication-graph-cohort-2026-09-04.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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