Article
A PI3 kinase inhibitor found to activate bestrophin 3.
Journal of cardiovascular pharmacology - 1 Jan 2010
Qu Zhiqiang, Han Xiaohua, Cui Yuanyuan, Li Chunlin
Abstract excerpt
Bestrophin 3 (Best3), a member of bestrophin Cl channel family, is a CaCl(cGMP) channel candidate in vascular smooth muscle cells. The mechanism for its activation remains unclear. In previous studies, we reported that an autoinhibitory domain ((356)IPSFLGS(362)) existed in Best3 C-terminus and w...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
