Article
Molecular determinations of EGFR and EML4-ALK on a single slide of NSCLC tissue.
Journal of clinical pathology - 1 Aug 2013
Ulivi Paola, Puccetti Maurizio, Capelli Laura, Chiadini Elisa, Bravaccini Sara, Calistri Daniele, Zoli Wainer, Amadori Dino, Candoli Piero
Abstract excerpt
INTRODUCTION: Tyrosine kinase inhibitors (TKIs) and anti-anaplastic lymphoma kinase (ALK) agents are highly effective for the treatment of non-small cell lung cancer (NSCLC) patients harbouring specific alterations, and molecular characterisation of the tumour is needed even when limited tumour material is available. METHODS: 20 patients with a known epidermal growth factor receptor (EGFR) gene status were...
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