Article
Detection of EML4-ALK fusion genes in a few cancer cells from transbronchial cytological specimens utilizing immediate cytology during bronchoscopy.
Lung cancer (Amsterdam, Netherlands) - 1 Aug 2012
Kanaji Nobuhiro, Bandoh Shuji, Ishii Tomoya, Tadokoro Akira, Watanabe Naoki, Takahama Takayuki, Haba Reiji, Imataki Osamu, Dobashi Hiroaki, Matsunaga Takuya
Abstract excerpt
The presence of fusion genes between the anaplastic lymphoma kinase (ALK) and echinoderm microtubule-associated protein-like 4 (EML4) genes is useful for determining appropriate molecular-targeted therapies in patients with non-small cell lung cancer (NSCLC). The diagnosis of NSCLC is often judge...
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