Article
EGFR mutation genotyping and ALK status determination in liquid-based cytology samples of non-small cell lung cancer.
Virchows Archiv : an international journal of pathology - 1 May 2020
Satoh Yukitoshi, Matsuo Yukiko, Kuba Tatsuru, Yamashita Kazuya, Sawano Mariko, Tozaka Shusaku, Yamazaki Hirotsugu, Sonoda Dai, Mikubo Masashi, Naito Masahito, Matsui Yoshio, Shiomi Kazu, Yoshida Tsutomu, Murakumo Yoshiki
Abstract excerpt
Personalised medicine for primary lung cancers (PLCs) requires molecular analysis of cancer tissue or cells. The primary objective of the present prospective study was to assess the concordance between epidermal growth factor receptor (EGFR) gene mutation detection and echinoderm microtubule-associated protein-like (EML) 4-anaplastic lymphoma kinase protein (ALK) expression using liquid-based cytology (LBC)...
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