Article
Comprehensive epidermal growth factor receptor gene analysis from cytological specimens of non-small-cell lung cancers.
British journal of cancer - 15 Jan 2008
Savic S, Tapia C, Grilli B, Rufle A, Bihl M P, de Vito Barascud A, Herzog M, Terracciano L, Baty F, Bubendorf L
Abstract excerpt
Epidermal growth factor receptor (EGFR) gene mutations and increased copy numbers are considered as predictors of response to EGFR tyrosine kinase inhibitors (EGFR-TKI) in non-small-cell lung cancer (NSCLC). Lung cancer diagnosis is often based on cytology alone. However, almost all published dat...
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