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Article

Interaction of estrogen receptor β and negative life events in susceptibility to major depressive disorder in a Chinese Han female population.

Journal of affective disorders - 15 Jan 2017

Zhang Jian, Chen Lu, Ma Jingsong, Qiao Zhengxue, Zhao Mingzhe, Qi Dong, Zhao Yan, Ban Bo, Zhu Xiongzhao, He Jincai, Yang Yanjie, Pan Hui

Abstract excerpt

BACKGROUND: Both genetic and environmental factors as well as their interaction contribute to the etiology of major depressive disorder (MDD). Estrogen receptor β (ESR2) may play a vital role in the development of MDD in females. The aim of this study is to analyze ESR2 gene polymorphisms and the interaction of ESR2 gene variation and negative life events concerning the risk of developing MDD in females,...

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Source

Identifiers

PMID: 27814959
DOI: 10.1016/j.jad.2016.08.083

Genes

ESR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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