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Article

Influence of the interaction between the serotonin 1A receptor C-1019G polymorphism and negative life stressors on the development of depression.

Neuropsychobiology - 1 Jan 2011

Kim Ha Kyoung, Kim Seog Ju, Lee Yu Jin, Lee Heon-Jeong, Kang Seung-Gul, Choi Jung-Eun, Yun Kyu-Wol, Lim Weon-Jeong

Abstract excerpt

The current study aimed to investigate the interaction between the serotonin 1A receptor gene (HTR1A) C-1019G polymorphism and recent negative life stressors on depression in a Korean community sample. The HTR1A C-1019G polymorphism was genotyped in 416 community-dwelling Koreans (156 males, 260 females; 44.37 ± 14.67 years old). Lifetime and current major depressive episodes were diagnosed using the Structured...

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PMID: 21577007
DOI: 10.1159/000322144

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