Article
Interaction between CRHR1 gene and stressful life events predicts adolescent heavy alcohol use.
Biological psychiatry - 15 Jan 2008
Blomeyer Dorothea, Treutlein Jens, Esser Günter, Schmidt Martin H, Schumann Gunter, Laucht Manfred
Abstract excerpt
BACKGROUND: Recent animal research suggests that alterations in the corticotropin releasing hormone receptor 1 (CRHR1) may lead to heavy alcohol use following repeated stress. The aim of this study was to examine interactions between two haplotype-tagging single nucleotide polymorphisms (SNPs) covering the CRHR1 gene and adverse life events on heavy drinking in adolescents. METHODS: Data were available from the...
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