ALCAM--novel multiple sclerosis locus interfering with HLA-DRB1*1501.

doi:10.1016/j.jneuroim.2013.02.015

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Article

ALCAM--novel multiple sclerosis locus interfering with HLA-DRB1*1501.

Journal of neuroimmunology - 15 May 2013

Wagner Marta, Wiśniewski Andrzej, Bilińska Małgorzata, Pokryszko-Dragan Anna, Nowak Izabela, Kuśnierczyk Piotr, Jasek Monika

Abstract excerpt

Activated leukocyte cell adhesion molecule (ALCAM) is a molecule involved in leukocyte migration across the blood-brain barrier which is a key stage in multiple sclerosis (MS) pathogenesis. The present study is the first to report evidence of the association of rs6437585 ALCAM polymorphism with risk and progression of MS. Our investigation revealed that rs6437585CT individuals had higher risk of MS (OR=2.34;...

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PMID: 23507476
DOI: 10.1016/j.jneuroim.2013.02.015

Genes

ALCAM

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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